{"entity":{"id":"parkinsons-disease-dementia","kind":"cancer","name":"Parkinson’s disease dementia","aka":[],"tldr":"Parkinson’s disease dementia is dementia that appears in the setting of established Parkinson’s disease. Rivastigmine has an FDA indication for this use and is a symptom treatment, not disease-modifying.","summary":"When dementia develops after established Parkinson’s disease, clinicians may diagnose Parkinson’s disease dementia. Overlap with dementia with Lewy bodies is biological. Rivastigmine is labeled in the US for mild-to-moderate dementia associated with Parkinson’s disease. Movement, sleep, hallucinations, and blood-pressure changes still shape the care plan.","asOf":"2026-09-21","wikipedia":"https://en.wikipedia.org/wiki/Parkinson%27s_disease_dementia","links":[{"label":"NICE NG97","url":"https://www.nice.org.uk/guidance/ng97"}],"tags":["dementia-atlas"],"related":["dementia-with-lewy-bodies"],"cancers":[],"sections":[],"technologies":[],"targets":["da-target-alpha-synuclein","da-target-ache"],"drugs":["da-rivastigmine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"group":"dementia","subtypes":[],"biomarkers":[],"standardOfCare":[{"setting":"Cognitive symptoms","approach":"Rivastigmine may be considered. Coordinate with the movement-disorder plan and avoid harmful antipsychotics where possible.","refs":["da-rivastigmine"],"guideline":{"version":"FDA rivastigmine labeling; NICE NG97","url":"https://www.nice.org.uk/guidance/ng97"}}],"stateOfArt":[],"history":[],"pipeline":[],"openProblems":[],"parent":"dementia"},"route":"/diagnoses/parkinsons-disease-dementia/","neighbours":{"cancer":[{"id":"dementia","kind":"cancer","name":"Dementia (umbrella)","route":"/diagnoses/dementia/"},{"id":"dementia-with-lewy-bodies","kind":"cancer","name":"Dementia with Lewy bodies","route":"/diagnoses/dementia-with-lewy-bodies/"}],"target":[{"id":"da-target-ache","kind":"target","name":"Acetylcholinesterase","route":"/targets/da-target-ache/"},{"id":"da-target-alpha-synuclein","kind":"target","name":"Alpha-synuclein","route":"/targets/da-target-alpha-synuclein/"}],"drug":[{"id":"da-rivastigmine","kind":"drug","name":"Rivastigmine","route":"/drugs/da-rivastigmine/"}]}}