ideas
ideas
Hypotheses and new directions, linked to the evidence.
3 ideas
| Bottleneck | Technologies | Diagnoses | ||||
|---|---|---|---|---|---|---|
Blood test before PET or lumbar puncture Use a blood test to decide who still needs a scan or spinal-fluid test, instead of sending everyone to PET. | Late and uneven diagnosis | Blood Alzheimer biomarkers | Alzheimer’s disease, Mild cognitive impairment | |||
Antibody trials that enrol mixed and comorbid disease Test amyloid antibodies in the mixed, comorbid people clinics actually see, instead of only in tidy trial cohorts. | Trial populations that skip mixed disease | none | Alzheimer’s disease, Mixed dementia | |||
Make carer outcomes a primary trial endpoint Judge dementia treatments by whether households cope better, not only by a clinic memory score. | Unpaid care as the hidden delivery system | none | none |