Alpha-synuclein
Alpha-synuclein is the protein in Lewy bodies. There is no approved treatment that clears it in dementia.
Overview
Disease-modifying synuclein programmes are research, not standard care.
- Target · the protein and the cell it sits on
- Drug · antibody, small molecule, cell or radioligand
- Effect · signal, damage or kill
In plain words · Alpha-synuclein is the protein in Lewy bodies. There is no approved treatment that clears it in dementia.
- 1 · What it is
Alpha-synuclein is the protein in Lewy bodies. There is no approved treatment that clears it in dementia.
- 2 · What goes wrong in cancer
Presynaptic protein that aggregates in Lewy bodies.
- 3 · How drugs use it
No product in this corpus aims at Alpha-synuclein yet. Drugs bind the molecule precisely: to switch it off, flag the cell for the immune system, or deliver a payload.
External identifiers
Biology
Presynaptic protein that aggregates in Lewy bodies.
Latest papers
topQuery for this target: (TITLE:"Alpha-synuclein" OR ABSTRACT:"Alpha-synuclein" OR TITLE:"SNCA" OR ABSTRACT:"SNCA") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Alpha-synuclein, not a curated reading list.
Similar pages
not linked directly; found by shared links- TreatmentRivastigmine
Shares Parkinson’s disease dementia, Dementia with Lewy bodies and the tag dementia-atlas.
- TargetAcetylcholinesterase
Shares Parkinson’s disease dementia, Dementia with Lewy bodies and the tag dementia-atlas.
- TechnologyCholinesterase inhibitors
Shares Dementia with Lewy bodies and the tag dementia-atlas.
- DiagnosisDementia (umbrella)
Shares Parkinson’s disease dementia, Dementia with Lewy bodies and the tag dementia-atlas.
- BottleneckWrong-subtype treatment
Shares Dementia with Lewy bodies and the tag dementia-atlas.